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Northeastern University
Pharmacology For The Health Professions (PHSC 4340)
Topically- none
Intranasal-burning of mucosa,
rebound congestion
Ophthalmic- narrow-angle
glaucoma
High dose = reflex bradycardia
Tremor, anxiety, restlessness
may occur due to stimulation
of CNS; increase HR and BP
Alpha-adrenergic
antagonist
Rapid decrease in
peripheral resistance,
reduces BP; treats
hypertension
Orthostatic hypotension; low
dose and at bed time; reflex
tachycardia due to decrease
in BP
N/A
C
Safety during
pregnancy and
lactation is not
established
Do not use
saw palmetto
or nettle root
products
Bethanechol
Ch. 13
Nonobstructive
urinary retention
agent
Direct-acting
Parasympathomimeti
c
Muscarinic cholinergic
Actions of
parasympathetic
stimulation;
stimulates smoothmuscle
contraction;
treats nonobstructive
urinary retention
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